From Empire Center:
Upstate New York’s population began to decline at a faster rate between mid-2014 and 2015, according to updated Census Bureau estimates.
As of last July 1, the 50 counties north of the mid-Hudson Valley had a combined population of 6,307,573—down 17,623 from the Census Bureau estimate of a year earlier. The drop in 2014-15 alone exceeded the population decrease in the previous four years, bringing the total population decline since the 2010 census to 31,740 people, or 0.5 percent. By contrast, upstate New York’s population increased by 52,074, or 0.8 percent, between 2000 and 2010.